Neutron scattering reveals human pyruvate dehydrogenase complex organisation

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Regulation of the human pyruvate dehydrogenase complex.

1. The pyruvate dehydrogenase complex from human heart has been partially purified and shown to be regulated by a phosphorylation-dephosphorylation cycle similar to that previously found for other mammalian tissues. 2. Incubation of the complex with ATP (2 mmol/1) led to its inactivation associated with the concomitant incorporation into the protein of 32P from the terminal phosphate group of t...

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ژورنال

عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography

سال: 2011

ISSN: 0108-7673

DOI: 10.1107/s0108767311095511